Our subject is genetic imprinting --though the Scientific American article is titled "Parental imprinting", and the third paragraph specifically says that the phenomenon in question is "called genome imprinting"; as we'll see, another term that shows up in the literature is genomic imprinting.
We'll begin with ANNIE, figuring that it's a likely source:
a W (keyword) search for 'genome imprinting' yields this:
GENOME is in 27 titles. IMPRINTING is in 10 titles. Both "IMPRINTING" and "GENOME" are in 0 title. Therefore "GENOME" is discarded. There are 8 entries with IMPRINTING. Do you want to see items found? (y/n)Sure, let's look:
You searched for the KEYWORD: genome imprinting W&L CATALOG 8 entries found, entries 1-8 are: LOCATIONS 1 Attachment of the young: imprinting and other d LEYBURN 2 Genomic imprinting : papers presented at a meet LEYBURN 3 Imprinting LEYBURN 4 Imprinting and cortical plasticity : comparativ LEYBURN 5 Imprinting and early learning LEYBURN 6 Imprinting; early experience and the developmen LEYBURN 7 Kin recognition LEYBURN 8 Olfactory imprinting and homing in salmon : inv LEYBURNA glance through these 8 quickly tells us that the main usage of "imprinting" has to do with parental identification --ducklings following their mother, not what we're conccerned with-- but the second item does seem relevant:
TITLE Genomic imprinting : papers presented at a meeting of the British Society for Developmental Biology at the University of Manchester, April 1990 / edited by Marilyn Monk and Azim Surani. PUBLISHER Cambridge, [England] : Company of Biologists, c1990. DESCRIPT 155 p. : ill. (some col.) ; 29 cm. SUBJECT Gene expression --Congresses. LOCATION CALL NO. 1 > Leyburn Library QH450 .G466 1990Yes, we'd probably want to look at that one, if only to check out the bibliographies accompanying the papers. But it is the collected papers from a conference, and thus isn't likely to be a very good starting place.
You searched for the WORD: genome imprinting PERIODICAL ABSTRACTS AUTHOR Peterson, Karen. TITLE Imprinting the genome : Imprinted genes, imprinting genes, and a hypothesis for their interaction. APPEARS IN Annual Review of Genetics 1993, v27, p. 7-31. SUMMARY Genetic and molecular evidence is presented for the existence of imprinted endogenous genes. The next step in imprinting research is to identify and isolate imprinting genes. SUBJECT Genetics. Genes. Holdings: ANNUAL REVIEW OF GENETICS 1 > Leyburn Library QH431.A1 A54 LIB HAS: 1(1967)-OK --Annual Reviews come in VERY handy for access to literature on a subject, since their purpose is to summarize what's been done. Clearly this one is a must-read, and its date (1993) means that its contents will be reasonably current. Its bibliography (135 items) is a fertile source for terminology, and the text itself
...summarize(s) the evidence for imprinting of both introduced and endogenous genes. The evidence leads to a model for the imprinting process and to predictions of how imprinting is involved in the expression of many disease phenotypes. We also make predictions about the function of imprinting proteins and discuss the ongoing search for imprinting genes. Finally, we consider the evolution of imprinting and its implications for the developing embyo. [pg. 8]
You searched for the WORD: genetic imprinting PERIODICAL ABSTRACTS 2 entries found, entries 1-2 are: APPEARS IN DATE 1 Genomic Imprinting in Hereditary Glom Lancet Dec 89 2 Genetic Imprinting Suggested by Mater Nature Nov 89 ----- AUTHOR van der Mey, Andel G L. TITLE Genomic Imprinting in Hereditary Glomus Tumors : Evidence for New Genetic Theory. APPEARS IN Lancet 1989, n8675, Dec 2, p. 1291-1294. SUMMARY A study showed that familial glomus tumors are inherited almost exclusively via the paternal line, a finding inconsistent with autosomal dominant transmission. Genomic imprinting may have considerable implications for genetic counseling with respect to glomus tumors and also for the understanding of other hereditary diseases. W&L does not own this periodical. Consult a librarian about availability.(incidentally, The Lancet is now available via Lexis/Nexis)
---- AUTHOR Nicholls, Robert D. TITLE Genetic Imprinting Suggested by Maternal Heterodisomy in Nondeletion Prader-Willi Syndrome. APPEARS IN Nature 1989, v342n6247, Nov 16, p. 281-285. SUMMARY Research has concluded that a gene or genes in region 15q11q13 must be inherited from each parent for normal human development. Individuals with a mutation in a specific gene such as in Prader-Willi syndrome are compared to those with normal genetic structure. Holdings: NATURE 1 > Leyburn Library PERIODICALS LIB HAS: 46(1892)-51(1894/95),53(1895/96)-103(1919),183(1959)-These two are perhaps useful, though not very current; we learn some handy facts and bits of terminology to add to our searching strategy.
You searched for the WORD: parental imprinting PERIODICAL ABSTRACTS 7 entries found, entries 1-7 are: APPEARS IN DATE 1 Allele-specific parental imprinting o Proceedings of the Nation May 94 2 Parental imprinting studied by allele Proceedings of the Nation Nov 92 3 Genomic imprinting : Parental origin Alcohol Health & Research Jan 92 4 Embryological and Molecular Investiga Nature Jun 91 5 Parental Imprinting of the Mouse H19 Nature May 91 6 Parental Imprinting of Genes Scientific American Oct 90 7 Genomic Imprinting Determines Methyla Nature Jul 87pAhah! not only do we find the Sci Am article, but there are also several more recent items:
Record 1 of 7 AUTHOR Chaudhuri, Sumita. TITLE Allele-specific parental imprinting of drz1, a posttranscriptional regulator of zein accumulation. APPEARS IN Proceedings of the National Academy of Sciences of the United States of America 1994, v91n11, May 24, p. 4867-4871. SUMMARY Parental imprinting is the phenomenon of unequivalent gene function based on the transmission from the female or male parent. Parental imprinting has been discovered on an allele of the drz1 locus that posttranscriptionally regulates the accumulation of 10-kDa zein in the maize endosperm. Holdings: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED 1 > Leyburn Library PERIODICALS LIB HAS: 61(1978)- ----- AUTHOR Singer-Sam, Judith. TITLE Parental imprinting studied by allele-specific primer extension after PCR : Paternal X chromosome-linked genes are transcribed prior to preferential paternal X chromosome inactivation. APPEARS IN Proceedings of the National Academy of Sciences of the United States of America 1992, v89n21, Nov 1, p. 10469-10473. SUMMARY A study sought to determine whether the paternal allele of the X chromosome-linked gene for 3-phosphoglycerate kinase 1 (Pgk-1), which is located near the center of X chromosome inactivation, is transcribed prior to differentiation of extraembryonic lineages. Results obtained by use of a reverse transcrption/ PCR-based method which allows the quantitative measurement of allele-specific RNA are discussed. ----- AUTHOR Kirkness, Ewen F. TITLE Genomic imprinting : Parental origin effects on gene expression. APPEARS IN Alcohol Health & Research World 1992, v16n4, p. 312-316. SUMMARY Certain genes seem to be imprinted, meaning that they can be differentially expressed depending on whether that gene is derived from the male or the female parent. This phenomenon and the mechanisms that produce it are discussed. SUBJECT Research. Genetics. Holdings: ALCOHOL HEALTH & RESEARCH WORLD 1 > Leyburn Library PERIODICALS LIB HAS: 14(1990)- ----- AUTHOR Ferguson-Smith, A C. TITLE Embryological and Molecular Investigations of Parental Imprinting on Mouse Chromosome 7. APPEARS IN Nature 1991, v351n6328, Jun 20, p. 667-670. SUMMARY Mouse embryos with duplications of whole maternal or paternal genomes show reciprocal phenotypes and do not develop to term. Now, the incorporation of cells with the paternal duplication into chimaeras, resulting in a striking growth enhancement of the embryos, has been discovered. AUTHOR Bartolomei, Marisa S. TITLE Parental Imprinting of the Mouse H19 Gene. APPEARS IN Nature 1991, v351n6322, May 9, p. 153-155. SUMMARY An RNase protection assay that can distinguish between H19 alleles in four subspecies of Mus is used to demonstrate that the H19 gene is parentally imprinted with the active copy derived from the mother. ----- AUTHOR Reik, Wolf. TITLE Genomic Imprinting Determines Methylation of Parental Alleles in Transgenic Mice. APPEARS IN Nature 1987, v328n6127, Jul 16, p. 248-251. SUMMARY Mouse embryogenesis research suggests that modifications are imprinted onto the chromosomes during gametogenesis. Genomic imprinting in transgenic mice is discussed.Quite a harvest, even for something as limited as Periodical Abstracts Online, which has only about 1500 peridoicals in its database. The Kirkness article looks like it would be fairly general, while most of the others are clearly from the research literature, and might be difficult to read without a good deal of background.
GENOMIC 2266 ITEMS UnCover GENOMIC + IMPRINTING 78 ITEMS GENOMIC + IMPRINTING 78 ITEMS UnCover 1 Szabo, Piroska E. (Genes & development. 08/01/95) Biallelic expression of imprinted genes in the mouse... 2 Chaillet, J. Richard (Genes & development. 05/15/95) Regulation of genomic imprinting by gametic and embr... 3 Vu, T. H. (The journal of clinical endocrino... 05/01/95) Insulin-Like Growth Factor II in Uterine Smooth-Musc... 4 Schachter, M. (Neurology. 05/01/95) Clinical evidence of genomic imprinting in Tourette'... **FAX 1HR* 5 Chatkupt, S. (Journal of the neurological scien... 05/01/95) Parents do matter: genomic imprinting and parental s... 6 Latham, Keith E. (Developmental biology. 04/01/95) Stage-Specific Induction and Regulation by Genomic I... 7 Guillemot, F. (Nature genetics. 03/01/95) Genomic imprinting of Mash2, a mouse gene required f... 8 Thomas, James H. (Proceedings of the National Academy 01/17/95) Genomic imprinting proposed as a surveillance mechan... 9 Stoll, C. (Annales de genetique. 1995 ) No evidence for genomic imprinting in liveborn Down 10 Cassidy, Suzanne B. (Environmental and molecular mutag... 1995 ) Uniparental Disomy and Genomic Imprinting as Causes **FAX 1HR* 11 Junien, Claudine (Kidney international. 11/01/94) Genetics of Wilms' tumor: A blend of aberrant develo... 12 Goshen, R. (Fertility and sterility. 11/01/94) The role of genomic imprinting in implanatation. 13 Weksberg, Rosanna (American journal of medical genet... 08/15/94) Letter to the Editor: Wiedemann-Beckwith Syndrome: G... 14 Rainer, S. (Journal of the National Cancer In... 07/06/94) Erratum: Genomic Imprinting, DNA Methylation, and Ca... (etc.) ----- PARENTAL 2759 ITEMS UnCover PARENTAL + IMPRINTING 36 ITEMS PARENTAL + IMPRINTING 36 ITEMS UnCover 1 Li, Xuri (Oncogene. 07/20/95) Expression, promoter usage and parental imprinting s... 2 Polychronakos, C. (Diabetologia. 06/01/95) Parental imprinting effect at the INS-IGF2 diabetes 3 Margaritte-Jeannin, (American journal of human genetics. 05/01/95) Testing Parental Imprinting in Insulin-Dependent Dia... 4 Chatkupt, S. (Journal of the neurological scien... 05/01/95) Parents do matter: genomic imprinting and parental s... 5 Sapienza, Carmen (American journal of human genetics. 12/01/94) Parental Origin Effects, Genome Imprinting, and Sex-... 6 Pedersen, R.A. (Nature genetics. 12/01/94) Parental imprinting of the Mas protooncogene in mous... 7 Singh, P.B. (Journal of cell science. 10/01/94) Molecular mechanisms of cellular determination: thei... 8 Riccio, Andrea (The journal of biological chemist... 09/30/94) Parental imprinting of rat insulin-like growth facto... 9 Chaudhuri, Sumita (Proceedings of the National Academy 05/24/94) Allele-specific parental imprinting of dzrl, a postg... 10 Ekstrom, T. J. (Hormone research. 1994 ) Parental Imprinting and the IGF2 Gene. 11 Ekstrom, T. J. (Hormone research. 1994 ) Parental Imprinting and the IGF2 Gene. 12 Xu, Yongqin (Biochemical and biophysical resea... 12/15/93) Functional Polymorphism in the Parental Imprinting o... 13 McFadden, D. E. (Human genetics. 11/01/93) Parental origin of triploidy in human fetuses: evide... 14 tada, T. (Genetical research. 10/01/93) parental imprinting on the mouse X chromosome: effec... ----- IMPRINTING + GENETIC 17 ITEMS IMPRINTING + GENETIC 17 ITEMS UnCover 1 Zerres, K. (Nephrology, dialysis, transplanta... 1995 ) On genetic heterogeneity, anticipation, and imprinti... **FAX 1HR* 2 Cassidy, Suzanne B. (Environmental and molecular mutag... 1995 ) Uniparental Disomy and Genomic Imprinting as Causes **FAX 1HR* 3 Zheng, Chang-Jiang (American journal of medical genet... 06/01/94) Allelic instability in mitosis can explain "Genome i... 4 Furtado, Sarah (American journal of medical genet... 05/15/94) Investigation of the Potential Role of Genetic Impri... 5 Asherson, P. (The british journal of psychiatry. 05/01/94) Imprinting and anticipation. Are they relevant to ge... 6 Cattanach, B. M. (Journal of inherited metabolic di... 1994 ) Genetic imprinting in the mouse: implications for ge... 7 Hochberg, A. (Medical hypotheses. 10/01/93) Genetic Imprinting in Human Evolution: The Decisive 8 Forejt, J. (Cell. 08/07/92) Genetic Analysis of Genomic Imprinting: An Imprintor... 9 Austin, Katherine Du (The Pediatric clinics of North Am... 04/01/92) Nontraditional Inheritance. 10 Pearce, Gavin P. (Genetics. 04/01/92) Population genetic models of genomic imprinting. 11 Farrar, Lindsay A. (The American journal of human gen... 03/01/92) Inverse Relationship between Age at Onset of Hunting... 12 Gregory, C.A. (Human genetics. ... 11/01/91) Somatic recombination rather than uniparental disomy... **FAX 1HR* 13 Farrer, Lindsay A. (Archives of neurology. 06/01/91) Association of Decreased Paternal Age an Late-Onset 14 Mann, J.R. (Cell. 07/27/90) Androgenetic Mouse Embryonic Stem Cells Are Pluripot... 15 Sved, John A. (American journal of human genetics. 03/01/90) Population Genetic Consequences of the Fragile-X Syn... 16 van der Mey, A.G.L. (The Lancet. 12/02/89) Genomic Imprinting in Hereditary Glomus Tumours: Evi... 17 Sapienza, C. (Development. 09/01/89) Epigenetic and genetic factors affect transgene meth...With these searches in UnCover we've clearly found more than we can use, so we can be choosy. Looking through the titles in these sets can greatly expand the understanding of the research landscape (what species? what recurring terms? what journals appear?)
Several immediate questions: