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FIELD Database:MEDLINE
FIELD Copyright:Copyright 2001 U.S. National Library of Medicine
FIELD Title:The last and the next hundred years of malariology
FIELD Author:Bradley D J
FIELD Corporate Source:London School of Hygiene and Tropical Medicine, UK.
FIELD Email Address:david.bradley@lshtm.ac.uk
FIELD Journal Title:PARASSITOLOGIA
FIELD Publication Date:1999 Sep
FIELD Volume:41
FIELD Issue:1-3
FIELD Page:11-8.
FIELD Reference Number:
FIELD Journal Code:OR7
FIELD Call Number:
FIELD Internat.Standard Doc. Number:0048-2951
FIELD Publication Country:Italy
FIELD Document Type:Historical; (LECTURES)
FIELD Language:English
FIELD Accession Number:2000162937
FIELD Abstract:The founding fathers of malariology combined scientific originality, perseverance in research, strong characters, breadth of interest and social concern. A hundred years later research and understanding has made immense progress but the world still bears a huge burden of malaria. For the next century research requires both more specialism and a holistic range if it is to be used in control, requiring multidisciplinary team work. Environmental changes and interventions produce a dynamic and changing pattern of malaria, not the static one of the past. From the original parasite life cycle, research has analysed a series of other cycles at electron microscope, biochemical and genome levels on decreasing size scales and quantitative epidemiological cycles for control. Recent additions to these concepts have been stage-specific antigens, cycles of disease rather than parasites alone, considering populations of parasites rather than just cases, and also genetic variation in each component of the parasite-human host-vector triad. In this volume there emerges for the first time a coherent overall picture of the biomedical aspects of basic malariology as the interacting population genetics of malaria parasites, anophelines and people. This provides a coherent model for the new century dealing with the great biological malaria problems of drug resistance, vaccine development, insecticidal and net control and can feed, with socio-economic work, into the gathering renewal of control efforts. New work on large-scale changes of malaria in space and time enables us to be precise about effects of local and global environmental changes to predict epidemics. Future research will be as much about linking these different scales of understanding as control will be about linking different levels of the health system. The grim situation in poor holoendemic countries also requires practical support of the type that the founders of malariology were involved in. A coherent understanding needs to feed into the new control efforts, from Roll Back Malaria onwards, for the next century.
FIELD Check Tags:Animal; Human
FIELD Supplementary Terms:
FIELD Mesh Headings: Anopheles; History of Medicine, 19th Cent.; History of Medicine, 20th Cent.; Italy; *Malaria: HI, history; Malaria: PC, prevention & control; *Parasitology: HI, history; Parasitology: TD, trends; Primary Prevention
FIELD CAS Registry Numbers:
FIELD Chemical Name:
FIELD Other Source:
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FIELD Database:MEDLINE
FIELD Copyright:Copyright 2001 U.S. National Library of Medicine
FIELD Title:The man who would conquer malaria
FIELD Author:Holloway M
FIELD Corporate Source:
FIELD Email Address:
FIELD Journal Title:SCIENTIFIC AMERICAN
FIELD Publication Date:1996 Dec
FIELD Volume:275
FIELD Issue:6
FIELD Page:52, 56.
FIELD Reference Number:
FIELD Journal Code:UGB
FIELD Call Number:
FIELD Internat.Standard Doc. Number:0036-8733
FIELD Publication Country:United States
FIELD Document Type:Biography; Historical; Journal; Article; (JOURNAL ARTICLE)
FIELD Language:English
FIELD Accession Number:97134496
FIELD Abstract:
FIELD Check Tags:Human
FIELD Supplementary Terms:
FIELD Mesh Headings: Colombia; History of Medicine, 20th Cent.; *Malaria: HI, history; Malaria: PC, prevention & control; *Malaria Vaccines: HI, history
FIELD CAS Registry Numbers:
FIELD Chemical Name:0 (Malaria Vaccines)
FIELD Other Source:
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FIELD Database:MEDLINE
FIELD Copyright:Copyright 2001 U.S. National Library of Medicine
FIELD Title:Creation of first malaria vaccine raises troubling questions about "intellectual racism" [interview by Kirsteen MacLeod]
FIELD Author:Patarroyo M
FIELD Corporate Source:
FIELD Email Address:
FIELD Journal Title:CMAJ
FIELD Publication Date:1995 Nov 1
FIELD Volume:153
FIELD Issue:9
FIELD Page:1319-21.
FIELD Reference Number:
FIELD Journal Code:CVV
FIELD Call Number:
FIELD Internat.Standard Doc. Number:0820-3946
FIELD Publication Country:Canada
FIELD Document Type:Biography; Historical; (INTERVIEW)
FIELD Language:English
FIELD Accession Number:96067017
FIELD Abstract:Some of the problems caused by malaria, which places a huge roadblock in front of economic progress in the Third World, may be solved by a new vaccine created by Dr. Manuel Patarroyo, a Columbian physician and researcher. "Imagine how things would be if Canadians had malaria," he says. "Episodes last 10 days, then there are 10 days of recovering. This leaves only 10 days each month in which to do some productive work. Then imagine killing the population of Toronto each year, and you can see the huge toll in terms of the number of yearly deaths globally from malaria." His discovery also raises the issue of "intellectual racism" because of criticism of Patarroyo's methods by Western scientists. Patarroyo, meanwhile, turned down a $60-million offer for his vaccine, and instead donated the patent to the World Health Organization.
FIELD Check Tags:Human
FIELD Supplementary Terms:
FIELD Mesh Headings:*Allergy and Immunology: HI, history; Attitude of Health Personnel; Colombia; History of Medicine, 20th Cent.; Jealousy; *Malaria Vaccines: HI, history; Portraits; *Protozoan Proteins: HI, history; Research
FIELD CAS Registry Numbers:
FIELD Chemical Name:0 (Malaria Vaccines); 0 (Protozoan Proteins); 0 (SPf66 protein)
FIELD Other Source:
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FIELD Database:MEDLINE
FIELD Copyright:Copyright 2001 U.S. National Library of Medicine
FIELD Title:Malaria control during the nineties: what is to be expected?
FIELD Author:van der Kaay H J
FIELD Corporate Source:Laboratory for Parasitology/Institute of Tropical Medicine, Faculty of Medicine/University of Leiden, The Netherlands.
FIELD Email Address:
FIELD Journal Title:ACTA LEIDENSIA
FIELD Publication Date:1991
FIELD Volume:60
FIELD Issue:1
FIELD Page:191-206.
FIELD Reference Number:
FIELD Journal Code:0WI
FIELD Call Number:
FIELD Internat.Standard Doc. Number:0065-1362
FIELD Publication Country:Netherlands
FIELD Document Type:Historical; Journal; Article; (JOURNAL ARTICLE)
FIELD Language:English
FIELD Accession Number:92320871
FIELD Abstract:
FIELD Check Tags:Female; Human; Male
FIELD Supplementary Terms:
FIELD Mesh Headings: History of Medicine, 20th Cent.; *Malaria: PC, prevention & control; Pregnancy; Protozoan Vaccines: HI, history
FIELD CAS Registry Numbers:
FIELD Chemical Name:0 (Protozoan Vaccines)
FIELD Other Source:
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FIELD Database:MEDLINE
FIELD Copyright:Copyright 2001 U.S. National Library of Medicine
FIELD Title:Steps towards a malaria vaccine
FIELD Author:Hommel M
FIELD Corporate Source:Department of Tropical Medicine and Infectious Diseases Liverpool, UK.
FIELD Email Address:
FIELD Journal Title:RESEARCH IN IMMUNOLOGY
FIELD Publication Date:1991 Oct
FIELD Volume:142
FIELD Issue:8
FIELD Page:618-31.
FIELD Reference Number:
FIELD Journal Code:R6E
FIELD Call Number:
FIELD Internat.Standard Doc. Number:0923-2494
FIELD Publication Country:France
FIELD Document Type:Historical; Journal; Article; (JOURNAL ARTICLE)
FIELD Language:English
FIELD Accession Number:92285524
FIELD Abstract:
FIELD Check Tags:Animal; Human
FIELD Supplementary Terms:
FIELD Mesh Headings: Antigens, Protozoan: IM, immunology; History of Medicine, 20th Cent.; Immunity, Active; Malaria: IM, immunology; *Malaria: PC, prevention & control; Plasmodium: IM, immunology; *Protozoan Vaccines: HI, history; Protozoan Vaccines: IM, immunology; Vaccines, Synthetic: IM, immunology; Vaccines, Synthetic: TU, therapeutic use
FIELD CAS Registry Numbers:
FIELD Chemical Name:0 (Antigens, Protozoan); 0 (Protozoan Vaccines); 0 (Vaccines, Synthetic)
FIELD Other Source:
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FIELD Database:MEDLINE
FIELD Copyright:Copyright 2001 U.S. National Library of Medicine
FIELD Title:Malaria control: present situation and need for historical research
FIELD Author:Najera J A
FIELD Corporate Source:Malaria Action Programme, World Health Organization, Geneva, Switzerland.
FIELD Email Address:
FIELD Journal Title:PARASSITOLOGIA
FIELD Publication Date:1990 Aug
FIELD Volume:32
FIELD Issue:2
FIELD Page:215-29.
FIELD Reference Number:24
FIELD Journal Code:OR7
FIELD Call Number:
FIELD Internat.Standard Doc. Number:0048-2951
FIELD Publication Country:Italy
FIELD Document Type:Historical; Journal; Article; (JOURNAL ARTICLE); General Review; (REVIEW); (REVIEW, TUTORIAL)
FIELD Language:English
FIELD Accession Number:92080332
FIELD Abstract:A rapid review is made of the history of malaria control, calling attention to differences between the evolution of the technical concepts, the formulated strategies and their implementation. Particular emphasis is placed on the discussion of the present situation of the world malaria problem and the difficulties faced by many endemic countries in adopting a malaria control strategy, based on primary health care, while their services are vertically organized for the performance of routines, which are irrelevant for disease control. The present malaria control strategy recognizes local variability, but it is possible to identify a limited number of types of situations, likely to respond to similar approaches. The definition not only of the control approaches but also of their conditions of applicability will become more precise as experiences are accumulated and adequately documented from different types of epidemiological situations. It is postulated that historical research on the malaria control and public health approaches, with proper attention being given to their socioeconomic and political context, in the countries which succeeded in controlling endemic malaria, will make an important contribution to such a definition.
FIELD Check Tags:Animal; Human
FIELD Supplementary Terms:
FIELD Mesh Headings: Africa; Antimalarials: HI, history; Antimalarials: TU, therapeutic use; Asia; Culicidae; Disease Outbreaks; Europe; Forecasting; History of Medicine, Ancient; History of Medicine, 19th Cent.; History of Medicine, 20th Cent.; Insect Vectors; Malaria: EP, epidemiology; Malaria: HI, history; *Malaria: PC, prevention & control; Mosquito Control; National Health Programs; Protozoan Vaccines; United States; World Health Organization
FIELD CAS Registry Numbers:
FIELD Chemical Name:0 (Antimalarials); 0 (Protozoan Vaccines); 0 (Vaccines)
FIELD Other Source:
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