Here's an example of a typical problem: you need to find out about
What do you do?
Clearly, the first problem is terminological, and its essence is that
this structure might have any of several names --all more or less
correct. You could start with what seems to be the easiest, searching by
its molecular formula:
C6H6O2
The online service ChemFinder (there's a link to
it on the Chemistry Dept. page) is a handy way to begin, and yields this
basic information:
Search produced 16 results:
Hydroquinone
Pyrocatechol
Resorcinol
2-Acetylfuran
5-methylfurfural
E,E-2,4-Hexadienedial
E,Z-2,4-Hexadienedial
Benzenediol
o-Benzosemiquinone
p-Benzosemiquinone
2,4-Hexadiyn-1,6-diol
Propargyl acrylate
Hexa-1,5-diene-3,4-dione
3-Cyclobutene-1,2-dione, 3,4-dimethyl-
Bicyclo[3.1.0]hexan-2,4-dione
1,4-Cyclohex-2-enedione
i.e., C6H6O2 is all of the
above. Turns out the one we want is Resorcinol, and here's what
Chemfinder gives us for that:
Resorcinol |
[108-46-3] |
Synonyms: Resorcin; m-dihydroxybenzene;
1,3-benzenediol; 1,3-Dihydroxybenzene; 3-Hydroxyphenol; C.I. 76505;
m-Hydroquinone; Eskamel |
and a bunch of physical properties, and then a bunch of links to various
databases in which the compound appears. A good beginning, especially
because we have THE KEY to finding more: the CAS Registry
Number[108-46-3]
There are other ways to think about naming this compound: it's a benzene
ring with two hydroxyls:- dihydric phenol?
- meta dihydric
phenol?
- dihydroxybenzene?
- 1,3-dihydroxybenzene?
- m-dihydroxybenzene?
Those all seem possible. In fact Chemical Abstracts knows it
as1,3-Benzenediol
but how would one
know that?
One wouldn't, though one would have to find it out in order to use
Chemical Abstracts to find out what had been written about the
compound. More on that below.
And we've already learned (thanks to ChemFinder) the "trivial"
name:
RESORCINOL.
Using Chemical Abstracts (now an almost-obsolete skill!!):
BEGIN with the Index Guide (updated every 4
years), which tells you for - Resorcinol
See 1,3-Benzenediol
[108-46-3]
In the (annual) Chemical Substances Index, under 1,3-Benzenediol,
you'll find listings of references to abstracts of articles (and
books and patents) having to do with uses, compounds, derivatives, analysis,
preparation, etc. etc.
Alternatively, you can use the Formula Index volumes (annual) to
find listings for C6H6O2 --but
there will probably be quite a few of them, and as we've seen, the
molecular formula applies to quite a few compounds.
Anyway, eventually you look in the Abstracts volumes to find brief
statements about the articles (etc.), including bibliographic information
that allows you to retrieve the articles (etc.) themselves.
I did a DIALOG ChemAbs search and found 8819 occurrences of 'resorcinol',
and 5477 occurrences of 'resorcinol' as a descriptor (i.e., in CA
records which are really "about" resorcinol. Here's a listing of the first 10 records (the most recently added to
the database), to give you an idea of what the online version is like.
Other routes to finding out about the compound involve various reference
books, such as:- Merck Index (Science-Reference RS51
.M4 1989)
- Kirk-Othmer Concise Encyclopedia of Chemical
Technology (Science-Reference TP9 .K54 1985)
- Dictionary of
Organic Compounds (Science-Reference QD246 .D5 1996)
- Dictionary of Drugs (Science-Reference RS51 .D479 1990) [for
compounds with pharmaceutical properties]
- Hazardous Chemicals Desk
Reference (Science-Reference T55.3 .H3 L49 1997)
Each of these offers a different sort of summary of materials on compounds.
The Patent Office offers another perspective. A quick search of the IBM
patent server turns up 531 hits, a number of them "process for manufacture
of...", and one can learn quite a lot from the 'state of the art' sections
of patents. The Patent Office yields 4 patents with 'resorcinol' in the
title in the last year, and 113 since 1976.
Another approach to finding out about resorcinol is to use a Web
search engine, and the results of such an exercise are
revealing. Something more than 2700 hits on AltaVista, many of them in
the .com realm (suppliers, manufacturers). Others have to do with
compounds in which resorcinol is
an actor (like resorcinol formaldehyde, a thermosetting resin, and
used in ion exchange resins [see a document on
cesium removal]) and
health considerations (diglycidyl resorcinol ether --an epoxy resin-- is a
carcinogen; some resorcinol derivatives are adrenoceptor agonists,
used as antiasthmatic agents). It turns out that there's a book
(Resorcinol: its uses and derivatives, Plenum Press, $239) on
"resorcinol's rapid development as a specialty chemical with broad-raning
applications in commerce and research..."). The point is: the Web
can often give us a quick idea of the broad significance of a chemical.