Mitochondrial genetics is a fascinating research frontier on several grounds: recent research has identified mtDNA mutations as the cause of a number of degenerative diseases (among them Huntington's Disease); evidence of the mitochondrial genome provides a sensitive measure for BOTH intraspecies and interspecies genetic variation --and is applicable to questions in forensics, in population ecology, and in studies of evolutionary divergence. This is hot stuff. Beginning with the nearest resources: If I do a keyword (W) search for 'mitochondrial dna' in Annie this is what I get: TITLE Evolution of life : fossils, molecules, and culture / S. Osawa, T. Honjo, (eds.) PUBLISHER Tokyo ; New York : Springer-Verlag, c1991. DESCRIPT xiii, 460 p. : ill. (some col.), map ; 25 cm. BIBLIOG. Includes bibliographical references and index. CONTENTS Fossils and evolution / P.D. Gingerich -- Biological extinction in terms of overadaptation / T. Hamada -- Revolutions and colonizations in the history of life / B. Halstead -- The genomic tag model for the origin of protein synthesis : further evidence from the molecular fossil record / A.M. Weiner and N. Maizels -- Neutral evolution / M. Kimura -- Recent evidence for evolution of the genetic code / T.H. Jukes and S. Osawa -- The grammatical rule of DNA language : messages in palindromic verses / S. Ohno -- Module organization in proteins and exon shuffling / M. Go -- Molecular evolution and the immunoglobulin gene superfamily / L. Hood and T. Hunkapiller. Evolution of the multigene family : a case of dynamically evolving genes at major histocompatibility complex / T. Ohta -- Evolution of a urea cycle enzyme to [delta]-crystallin / M. Mori ... [et al.] -- Evolution of repetitive sequences / N. Okada ... [et al.] -- Evolution of organellar genomes / K. Ohyama ... [et al.] -- Mechanisms of speciation : a review / W.B. Provine -- Comparing life histories / P.H. Harvey -- The seething genetics of health and the evolution of sex / W.D. Hamilton -- On the evolution of reproductive isolation and the origin of species / F.J. Ayala -- The evolution of cells / T. Cavalier-Smith -- Symbiosis in evolution : origins of cell motility / L. Margulis. Archaebacteria vs metabacteria : phylogenetic tree of organisms indicated by comparison of 5S ribosomal RNA sequences / H. Hori ... [et al.] -- Evolution of archaebacteria : phylogenetic relationships among archaebacteria, eubacteria, and eukaryotes / T. Miyata ... [et al.] -- Early biochemical evolution : speculations on the biochemistry of primitive life / T. Oshima -- Man, culture, and environment / P.V. Tobias -- The origin of the genus Homo / A. Walker -- Sequence evolution of mitochondrial DNA in humans and chimpanzees : control region and a protein-coding region / T.D. Kocher and A.C. Wilson -- Evolutionary relationships of human populations at the molecular level / M. Nei and T. Ota -- Human genome and human evolution / S. Ueda. Some theoretical aspects of the origin of cultural transmission / K. Aoki -- Summary and concluding remarks / S. Brenner. SUBJECT Life --Origin. Molecular evolution. Human evolution. Leyburn Library QH325 .E964 1991 +++++ That's not very encouraging, so I broaden the search considerably: You searched for the KEYWORD: mitochondr* 26 entries found, entries 1-8 are: LOCATIONS 1 Biochemistry and biophysics of mitochondrial me LEYBURN 2 Biochemistry of mitochondria : [papers] LEYBURN 3 The biogenesis of mitochondria: transcriptional LEYBURN 4 Cytoplasmic genes and organelles LEYBURN 5 Energy and the mitochondrion LEYBURN 6 Energy metabolism and the regulation of metabol LEYBURN 7 Evolution of life : fossils, molecules, and cul LEYBURN 8 Genetics and biogenesis of mitochondria and chl LEYBURN 9 Ion transport and intramitochondrial pH LEYBURN 10 The mammalian mitochondrial respiratory chain LEYBURN 11 Mammalian oogenesis; LEYBURN 12 Membrane biogenesis : mitochondria, chloroplast LEYBURN 13 Membranes of mitochondria and chloroplasts. LEYBURN 14 Mitochondria LEYBURN 15 Mitochondria LEYBURN 16 Mitochondria 1977 : genetics and biogenesis of LEYBURN 17 Mitochondria and microsomes : in honor of Lars LEYBURN 18 Mitochondria in higher plants : structure, func LEYBURN 19 The mitochondrion in health and disease LEYBURN 20 The mitochondrion; molecular basis of structure CHEMISTRY 21 The mitochondria of microorganisms LEYBURN 22 Mitochondria : structure, biogenesis, and trans LEYBURN 23 Mitochondria : structure, function, and assembl LEYBURN 24 Organelle heredity LEYBURN 25 Selected papers in biochemistry LEYBURN 26 The structure of mitochondria LEYBURN I might want to LIMIT this result to just fairly recent books. L is the LIMIT command: You may limit your search by any of the following L > LANGUAGE M > MATERIAL type T > Words in the TITLE A > Words in the AUTHOR S > Words in the SUBJECT P > PUBLISHER W > WHERE Item is located Y > YEAR of publication R > RETURN to Browsing Choose one (L,M,T,A,S,P,W,Y,R) and I choose Y for year: E > Equal to A > After B > Before R > RETURN to Previous Screen Choose one (E,A,B,R) and 1988 YEAR of publication AFTER 1988 F > Find items with above limits You searched for the KEYWORD: mitochondr* LIMITED TO AFTER 1988 2 entries found, entries 1-2 are: LOCATIONS 1 Evolution of life : fossils, molecules, and cul LEYBURN 2 The mitochondrion in health and disease LEYBURN This adds only one, but it looks like it might be interesting: AUTHOR Tyler, David D. TITLE The mitochondrion in health and disease / David D. Tyler. PUBLISHER New York, N.Y. : VCH, c1992. DESCRIPT xiv, 557 p. : ill. ; 24 cm. NOTE Cover and spine title: The mitochondrion in health & disease. BIBLIOG. Includes bibliographical references and index. SUBJECT Mitochondria. Leyburn Library QH603.M5 T93 1992 ++++++ But this search in Annie is somewhat disappointing --only ONE book that has 'mitochondrial dna' in its record. So what's the big deal? *part of the answer is that the literature on the subject is not really IN books, or anyway not nearly so much as it is in periodical literature, which we'll examine next week But it's worth looking at a larger library to see if we're missing something entirely. Here's what Harvard's HOLLIS yields: HU INDEX: LIST OF ITEMS RETRIEVED 13 items retrieved by your search: FIND KW MITOCHONDRIAL DNA --------------------------------------------------------------------------- BIOCHEMICAL AND GENETIC CHARACTERISTIZATION OF MSH1 A MITOCHONDRIAL PROTEIN OF SACCHAROMYCES CEREVISIAE THAT BINDS TO DNA MISMATCHES 1 chi nai wen/ 1994 bks MITOCHONDRIAL DNA IN HUMAN PATHOLOGY 2 dimauro s/ 1993 bks RNA EDITING AND THE EVOLUTION OF MITOCHONDRIAL DNA IN KINETOPLASTID PROTOZOA 3 landweber laura faye/ 1993 bks MITOCHONDRIAL DNA AND EVOLUTION A RECONSTRUCTION OF HOMINOID PHYLOGENY 4 pan deborah/ 1993 bks MITOCHONDRIAL GENOMES 5 wolstenholme david r/ 1992 bks SEQUENCE EVOLUTION OF THE MITOCHONDRIAL DNA D LOOP REGION IN CHIMPANZEES A STUDY OF GENETIC VARIABILITY IN PAN TROGLODYTES SUBSPECIES 6 viswanathan akila ninette/ 1991 bks MITOCHONDRIAL DNA EVOLUTION IN THE PEROMYSCUS LEUCOPUS SPECIES GROUP GENETIC STRUCTURE IN POPULATIONS WITHIN A HYBRID ZONE 7 nelson kimberlyn/ 1988 bks CHONDRIOME CHLOROPLAST AND MITOCHONDRIAL GENOMES 8 mantell s h/ 1986 bks MITOCHONDRIAL DNA VARIATION AND THE PHYLOGENY OF AFRICAN MOLE RATS RODENTIA BATHYERGIDAE 9 edwards scott v/ 1986 bks MITOCHONDRIAL GENES 10 borst piet/ 1982 bks ORGANIZATION AND EXPRESSION OF THE MITOCHONDRIAL GENOME PROCEEDINGS OF THE 12TH INTERNATIONAL BARI CONFERENCE ON THE ORGANIZATION AND EXPRESSION OF THE MITOCHON 11 international bari conference on the organization and expression/ 1980 bks MITOKHONDRIALNAIA DNK MITOCHONDRIAL DNA 12 gauze georgii georgievich/ 1977 bks GENETIC FUNCTION OF MITOCHONDRIAL DNA PROCEEDINGS OF THE INTERNATIONAL BARI CONFERENCE ON THE GENETIC FUNCTION OF MITOCHONDRIAL DNA RIVA DEI TESSALI ITALY 13 international bari conference on the genetic function of mitocho/ 1976 bks HU SHORT DISPLAY page 1 of 1 Item 1 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# AYA9887 /bks AUTHOR: Chi, Nai-Wen. TITLE: Biochemical and genetic characteristization of MSH1, a mitochondrial protein of Saccharomyces cerevisiae that binds to DNA mismatches / a thesis presented by Nai-Wen Chi. PUB. INFO: 1994. DESCRIPTION: 150 leaves : ill. ; 29 cm. SUBJECTS: *S1 DNA. *S2 Mitochondrial DNA. *S3 Saccharomyces cerevisiae. HU SHORT DISPLAY page 1 of 1 Item 2 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# AVQ4061 /bks TITLE: Mitochondrial DNA in human pathology / editors, Salvatore DiMauro, Douglas C. Wallace. PUB. INFO: New York : Raven Press, c1993. DESCRIPTION: x, 206 p. : ill. ; 25 cm. SUBJECTS: *S1 Mitochondrial DNA--Abnormalities. MED. SUBJECTS: *M1 DNA, Mitochondrial--genetics--congresses. *M2 Mitochondria--pathology--congresses. HU SHORT DISPLAY page 1 of 1 Item 3 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# AQR5795 /bks AUTHOR: Landweber, Laura Faye. TITLE: RNA editing and the evolution of mitochondrial DNA in kinetoplastid protozoa / Laura Faye Landweber. PUB. INFO: 1993. DESCRIPTION: iii, 45 leaves : ill. ; 29 cm. SUBJECTS: *S1 Kinetoplastida. *S2 Mitochondrial DNA. *S3 Molecular evolution. HU SHORT DISPLAY page 1 of 1 Item 4 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# APM5185 /bks AUTHOR: Pan, Deborah. TITLE: Mitochondrial DNA and evolution : a reconstruction of hominoid phylogeny / by Deborah Pan. PUB. INFO: 1993. DESCRIPTION: viii, 121 leaves ; 28 cm. SUBJECTS: *S1 Mitochondrial DNA. *S2 Evolution (Biology) *S3 Orangutan. *S4 Gorilla. HU SHORT DISPLAY page 1 of 1 Item 5 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# ANU7486 /bks TITLE: Mitochondrial genomes / guest edited by David R. Wolstenholme [and] Kwang W. Jeon. PUB. INFO: San Diego : Academic Press, c1992. DESCRIPTION: xii, 377 p. : ill. ; 24 cm. SERIES: International review of cytology ; v. 141 SUBJECTS: *S1 Mitochondria. *S2 Cytoplasmic inheritance. *S3 Extrachromosomal DNA. HU SHORT DISPLAY page 1 of 1 Item 6 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# ANM5500 /bks AUTHOR: Viswanathan, Akila Ninette. TITLE: Sequence evolution of the mitochondrial DNA D-loop region in chimpanzees : a study of genetic variability in Pan troglodytes subspecies / by Akila Ninette Viswanathan. PUB. INFO: 1991. DESCRIPTION: iii, 55, iii, ii leaves : ill. ; 29 cm. SUBJECTS: *S1 Chimpanzees--Evolution. *S2 Chimpanzees--Genetics. *S3 Chimpanzees--Variation. HU SHORT DISPLAY page 1 of 2 Item 7 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# AIQ9940 /bks AUTHOR: Nelson, Kimberlyn. TITLE: Mitochondrial DNA evolution in the Peromyscus leucopus species group : genetic structure in populations within a hybrid zone / by Kimberlyn Nelson. PUB. INFO: 1988. DESCRIPTION: 1 v. (various foliations) : ill. ; 29 cm. SUBJECTS: *S1 Peromyscus leucopus. *S2 Molecular evolution. *S3 Population genetics. *S4 Extrachromosomal DNA. HU SHORT DISPLAY page 1 of 1 Item 8 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# AGY7796 /bks TITLE: The Chondriome : chloroplast and mitochondrial genomes / edited by S.H. Mantell, G.P. Chapman and P.F.S. Street. PUB. INFO: Harlow, Essex, England : Longman Scientific & Technical ; New York : J. Wiley & Sons, 1986. DESCRIPTION: 310 p. : ill. ; 25 cm. SERIES: Monographs and surveys in the biosciences SUBJECTS: *S1 Plant genetics. *S2 Extrachromosomal DNA. *S3 Cytoplasmic inheritance. HU SHORT DISPLAY page 1 of 1 Item 9 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# AEM8399 /bks AUTHOR: Edwards, Scott V. TITLE: Mitochondrial DNA variation and the phylogeny of African mole rats (Rodentia: Bathyergidae) / by Scott V. Edwards. PUB. INFO: 1986. DESCRIPTION: 147 leaves : ill. ; 28 cm. SUBJECTS: *S1 Bathyergidae--Evolution. *S2 Bathyergidae--Genetics. HU SHORT DISPLAY page 1 of 1 Item 10 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# AEQ7335 /bks TITLE: Mitochondrial genes / edited by Piotr Slonimski, Piet Borst, Giuseppe Attardi. PUB. INFO: Cold Spring Harbor, NY : Cold Spring Harbor Laboratory, 1982. DESCRIPTION: xviii, 500 p. : ill., ports. ; 24 cm. SERIES: Cold Spring Harbor monograph series ; 12 SUBJECTS: *S1 Mitochondria--Congresses. *S2 Extrachromosomal DNA--Congresses. MED. SUBJECTS: *M1 Mitochondria--congresses *M2 DNA, Mitochondrial--congresses HU SHORT DISPLAY page 1 of 2 Item 11 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# AEK2221 /bks AUTHOR: International Bari Conference on the Organization and Expression of the Mitochondrial Genome (12th : 1980 : Martina Franca, Italy). TITLE: The organization and expression of the mitochondrial genome : proceedings of the 12th International Bari Conference on the Organization and Expression of the Mitochondrial Genome held in Martina Franca, Italy, 23-28 June 1980 / editors, A.M. Kroon and C. Saccone. PUB. INFO: Amsterdam ; New York : Elsevier/North-Holland Biomedical Press ; New York, N.Y. : Sole distributors for the USA and Canada, Elsevier North Holland, 1980. DESCRIPTION: xi, 451 p. : ill. SERIES: Developments in genetics ; v. 2 MED. SUBJECTS: *M1 DNA, Mitochondrial--congresses *M2 Mitochondria--congresses HU SHORT DISPLAY page 1 of 1 Item 12 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# ANC9330 /bks AUTHOR: Gauze, Georgii Georgievich. TITLE: Mitokhondrial'naia DNK = [Mitochondrial DNA] / G.G. Gauze. PUB. INFO: Moskva : Nauka, 1977. DESCRIPTION: 288 p. : ill. NON-HARVARD LOCATION: CRL (Chicago): HU SHORT DISPLAY page 1 of 1 Item 13 of 13 retrieved by your search: FIND KW MITOCHONDRIAL DNA ------------------------------------------------------HU HOLLIS# ADO7876 /bks AUTHOR: International Bari Conference on the Genetic Function of Mitochondrial DNA, 10th, Riva dei Tessali, Italy, 1976. TITLE: The genetic function of mitochondrial DNA : proceedings of the International Bari Conference on the Genetic Function of Mitochondrial DNA, Riva dei Tessali, Italy, 25-29 May, 1976 / editors C. Saccone and A. M. Kroon. PUB. INFO: Amsterdam ; New York : North-Holland Pub. Co., 1976. DESCRIPTION: xiii, 354 p. : ill. ; 24 cm. SUBJECTS: *S1 Mitochondria--Congresses. *S2 DNA--Congresses. +++++++++++ This is better, in that it's possible to see that there's interesting research going on and being reported in books, but the real action is in periodical literatures, as we'll see.