Lexis/Nexis seems to be somewhat behind the FirstSearch version of MEDLINE (which gives 384 records for the 'genomic imprinting' search), but the searching language for Lexis/Nexis is much more flexible and powerful. The FirstSearch version is adequate for shotgun searches with simple terms, but once you are ready to do complex searches (seeking the work of particular researchers, or reducing large sets of results to essential articles) Lexis/Nexis is the preferred tool. A guide to searching Lexis/Nexis is available at the Reference Desk.
GENOMIC IMPRINTING Your search request has found 352 REFERENCES through Level 1. LEVEL 1 - 352 REFERENCES 1. Maintenance of normal imprinting of H19 and IGF2 genes in neuroblastoma., Wada M; Seeger RC; Mizoguchi H; Koeffler HP, Cancer Res 1995 Aug 1; 55 (15): 3386-8 2. Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: uncoupling of IGF2 and H19 imprinting., Li X; Adam G; Cui H; Sandstedt B; Ohlsson R; Ekstrom TJ, Oncogene 1995 Jul 20; 11 (2): 221-9 3. Patterns of maternal transmission in bipolar affective disorder [see comments]., McMahon FJ; Stine OC; Meyers DA; Simpson SG; DePaulo JR, Am J Hum Genet 1995 Jun; 56 (6): 1277-86 4. Extensive mtDNA diversity in horses revealed by PCR-SSCP analysis., Marklund S; Chaudhary R; Marklund L; Sandberg K; Andersson L, Anim Genet 1995 Jun; 26 (3): 193-6 5. Two new variants of the bovine PAS-1 glycoprotein., Sacchi P; Macchi E; Rasero R; Fiandra P, Anim Genet 1995 Jun; 26 (3): 197-8 6. Partial deletion of the Y chromosome removes the effect of paternal genome imprinting on periovum sensitivity to hyaluronidase in mice., Styrna J, Genet Res 1995 Jun; 65 (3): 229-31 7. Turner syndrome and female sex chromosome aberrations: deduction of the principal factors involved in the development of clinical features., 110 REFS, Ogata T; Matsuo N, Hum Genet 1995 Jun; 95 (6): 607-29 8. Regulation of genomic imprinting by gametic and embryonic processes., Chaillet JR; Bader DS; Leder P, Genes Dev 1995 May 15; 9 (10): 1177-87 9. Longitudinal observations on 15 children with Wiedemann-Beckwith syndrome., Weng EY; Moeschler JB; Graham JM Jr, Am J Med Genet 1995 May 8; 56 (4): 366-73 10. Genomic imprinting. Action at a distance [news; comment]., Eden S; Cedar H, Nature 1995 May 4; 375 (6526): 16-7 11. Disruption of imprinting caused by deletion of the H19 gene region in mice [see comments]., Leighton PA; Ingram RS; Eggenschwiler J; Efstratiadis A; Tilghman SM, Nature 1995 May 4; 375 (6526): 34-9 12. Testing parental imprinting in insulin-dependent diabetes mellitus by the marker-association-segregation-chi 2 method., Margaritte-Jeannin P; Clerget-Darpoux F; Hors J; Deschamps I, Am J Hum Genet 1995 May; 56 (5): LEVEL 1 - 352 REFERENCES 13. Molecular definition of deletions of different segments of distal 5p that result in distinct phenotypic features., Church DM; Bengtsson U; Nielsen KV; Wasmuth JJ; Niebuhr E, Am J Hum Genet 1995 May; 56 (5): 1162-72 14. Loss of imprinting in hepatoblastoma., Rainier S; Dobry CJ; Feinberg AP, Cancer Res 1995 May 1; 55 (9): 1836-8 15. Insulin-like growth factor II in uterine smooth-muscle tumors: maintenance of genomic imprinting in leiomyomata and loss of imprinting in leiomyosarcomata.Vu TH; Yballe C; Boonyanit S; Hoffman AR, J Clin Endocrinol Metab 1995 May; 80 (5): 1670-6 16. Clinical evidence of genomic imprinting in Tourette's syndrome., Lichter DG;Jackson LA; Schachter M, Neurology 1995 May; 45 (5): 924-8 17. ["... One egg like the other?" The genetic variability of monozygotic twins and its possible effect on concordance studies in immunological diseases (editorial)]., "... wie ein Ei dem anderen?" Die genetische Variabilitat von eineiigen Zwillingen und ihr moglicher Einfluss auf Konkordanzstudien bei immunologischen Erkrankungen., Keysser G; Burmester GR, Dtsch Med Wochenschr 1995 Apr 21; 120 (16): 547-8.1 ======= LEVEL 1 - 2 OF 352 REFERENCES National Library of Medicine MEDLINE Database TITL: Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: uncoupling of IGF2 and H19 imprinting. AUTH: Li X; Adam G; Cui H; Sandstedt B; Ohlsson R; Ekstrom TJ ORGA: Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden. CITE: Oncogene 1995 Jul 20; 11 (2): 221-9 LANG: ENG; English ABST: We have studied the promoter utilization and parental imprinting status of human IGF2 in three genetically informative hepatoblastomas from patients ranging in age from 9 months to 3 years. In all three cases, there is a downregulation of promoter P1 in the tumor tissues while the P2 and P3 promoters are upregulated compared to the normal liver. One of three patients displayed loss of imprinting (LOI) of IGF2 in the tumor tissue. We also investigated the expression of the H19 gene in all three cases and the methylation pattern in H19 from the patient with LOI of IGF2. The expression of H19 was greatly reducedin all tumors. Monoallelic H19 expression however, was retained even in the casewhich showed LOI of IGF2. Unlike the situation in Wilms' tumor, no differences in the methylation pattern between the normal liver and tumor tissues were observed in the H19 promoter or 3' region, using HpII analysis. We show here, that in contrast to the situation in Wilms' tumor, H19 expression is not a prerequisite for maintaining a monoallelic IGF2 expression. (AUTHOR) MJTR: Gene Expression Regulation, Neoplastic. Genes, Suppressor, Tumor. Genomic Imprinting GE. Hepatoblastoma GE. Insulin-Like Growth Factor II GE. Liver Neoplasms GE. MNTR: Alleles. Base Sequence. Child, Preschool. Female. Human. Infant. Liver PH. Male. Methylation. Molecular Sequence Data. Promoter Regions (Genetics) GE. Support, Non-U.S. Gov't. Transcription,Genetic. JOURNAL ARTICLE RNUM: 67763-97-7 (Insulin-Like Growth Factor II) GEOT: ENGLAND IDEN: ISSN: 0950-9232. JOURNAL-CODE: ONC. ENTRY-DATE: 950831. JOURNAL-SUBSET: M X. IM-DATE: 9511. ACCE: 95349944 ===== GENOME IMPRINTING Your search request has found 26 REFERENCES through Level 1. LEVEL 1 - 26 REFERENCES 1. Partial deletion of the Y chromosome removes the effect of paternal genome imprinting on periovum sensitivity to hyaluronidase in mice., Styrna J, Genet Res 1995 Jun; 65 (3): 229-31 2. Genotype-specific modifiers of transgene methylation and expression in the zebrafish, Danio rerio., Martin CC; McGowan R, Genet Res 1995 Feb; 65 (1): 21-8 3. Parental origin effects, genome imprinting, and sex-ratio distortion: double or nothing? [editorial; comment]., Sapienza C, Am J Hum Genet 1994 Dec; 55 (6): 1073-5 4. Frequency of X-Y chromosome dissociation in mouse spermatocytes from interstrain crosses, recombinant inbred strains, and chimeras: possible involvement of paternal genome imprinting., Krzanowska H; Wabik-Sliz B, Mol Reprod Dev 1994 Dec; 39 (4): 347-54 5. On the oncodevelopmental role of human imprinted genes., 34 REFS, Biran H; Ariel I; De Groot N; Hochberg A, Med Hypotheses 1994 Aug; 43 (2): 119-23 6. Allelic instability in mitosis can explain "genome imprinting" and other genetic phenomena in psoriasis [letter; comment]., Zheng GJ; Thomson G; Pen YN, Am J Med Genet 1994 Jun 1; 51 (2): 163-4 7. Genomic imprinting -- defusing the ovarian time bomb [see comments]., VarmuzaS; Mann M, Trends Genet 1994 Apr; 10 (4): 118-23 8. Concordance between parental origin of chromosome 13q loss and chromosome 6p duplication in sporadic retinoblastoma., Naumova A; Hansen M; Strong L; Jones PA; Hadjistilianou D; Mastrangelo D; Griegel S; Rajewsky MF; Shields J; Donoso L; et al, Am J Hum Genet 1994 Feb; 54 (2): 274-81 9. Epigenetic inheritance in mammals., 45 REFS, Lyon MF, Trends Genet 1993 Apr; 9 (4): 123-8 10. [Parental genome imprinting]., L'empreinte genomique parentale., 27 REFS, Babinet C, Ann Genet 1993; 36 (1): 63-9 11. The polar-lethal Ovum mutant gene maps to the distal portion of mouse chromosome 11., Sapienza C; Paquette J; Pannunzio P; Albrechtson S; Morgan K, Genetics 1992 Sep; 132 (1): 241-6 12. Genome imprinting and cancer genetics., 48 REFS, Sapienza C, Semin Cancer Biol 1992 Jun; 3 (3): 151-8 ===== PARENTAL IMPRINTING Your search request has found 56 REFERENCES through Level 1. LEVEL 1 - 56 REFERENCES 1. Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: uncoupling of IGF2 and H19 imprinting., Li X; Adam G; Cui H; Sandstedt B; Ohlsson R; Ekstrom TJ, Oncogene 1995 Jul 20; 11 (2): 221-9 2. Testing parental imprinting in insulin-dependent diabetes mellitus by the marker-association-segregation-chi 2 method., Margaritte-Jeannin P; Clerget-Darpoux F; Hors J; Deschamps I, Am J Hum Genet 1995 May; 56 (5): 1080-7 3. Allelotype analysis of mouse lung carcinomas reveals frequent allelic losses on chromosome 4 and an association between allelic imbalances on chromosome 6 and K-ras activation., Hegi ME; Devereux TR; Dietrich WF; Cochran CJ; Lander ES;Foley JF; Maronpot RR; Anderson MW; Wiseman RW, Cancer Res 1994 Dec 1; 54 (23): 6257-64 4. Parental imprinting of the Mas protooncogene in mouse., Villar AJ; Pedersen RA, Nat Genet 1994 Dec; 8 (4): 373-9 5. Comparative analysis of Igf-2/H19 imprinted domain: identification of a highly conserved intergenic DNase I hypersensitive region., Koide T; Ainscough J; Wijgerde M; Surani MA, Genomics 1994 Nov 1; 24 (1): 1-8 6. The molecular basis for dominant yellow agouti coat color mutations., 39 REFSPerry WL; Copeland NG; Jenkins NA, Bioessays 1994 Oct; 16 (10): 705-7 7. Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes., Feil R; Walter J; Allen ND; Reik W, Development 1994 Oct; 120 (10): 2933-43 8. Molecular mechanisms of cellular determination: their relation to chromatin structure and parental imprinting., 150 REFS, Singh PB, J Cell Sci 1994 Oct; 107( Pt 10): 2653-68 9. Protective protein for beta-galactosidase, Ppgb, maps to the distal imprinting region of mouse chromosome 2 but is not imprinted., Williamson CM; Dutton ER; Beechey CV; Peters J, Genomics 1994 Jul 1; 22 (1): 240-2 10. Imprinting and X chromosome counting mechanisms determine Xist expression inearly mouse development., Kay GF; Barton SC; Surani MA; Rastan S, Cell 1994 Jun 3; 77 (5): 639-50 11. Allele-specific parental imprinting of dzr1, a posttranscriptional regulatorof zein accumulation., Chaudhuri S; Messing J, Proc Natl Acad Sci U S A 1994 May24; 91 (11): 4867-71